PhytophthoraV1, Main, Exploration, bibRecord, 000606

Phytophthora infestans RXLR Effectors Target Parallel Steps in an Immune Signal Transduction Pathway.

Identifieur interne : 000606 ( Main/Exploration ); précédent : 000605; suivant : 000607

Phytophthora infestans RXLR Effectors Target Parallel Steps in an Immune Signal Transduction Pathway.

Auteurs : Yajuan Ren [République populaire de Chine] ; Miles Armstrong [Royaume-Uni] ; Yetong Qi [République populaire de Chine] ; Hazel Mclellan ; Cheng Zhong [République populaire de Chine] ; Bowen Du [République populaire de Chine] ; Paul R J. Birch [Royaume-Uni] ; Zhendong Tian [République populaire de Chine]

Source :

Plant physiology [ 1532-2548 ] ; 2019.

RBID : pubmed:31217198

Descripteurs français

KwdFr :
- Feuilles de plante (microbiologie), Feuilles de plante (métabolisme), Immunité des plantes (physiologie), Lycopersicon esculentum (microbiologie), Lycopersicon esculentum (métabolisme), Maladies des plantes (microbiologie), Mort cellulaire (physiologie), Noyau de la cellule (microbiologie), Noyau de la cellule (métabolisme), Phytophthora infestans (pathogénicité), Protéines végétales (génétique), Protéines végétales (métabolisme), Tabac (microbiologie), Tabac (métabolisme), Transduction du signal (génétique), Transduction du signal (physiologie).
MESH :
- génétique : Protéines végétales, Transduction du signal.
- microbiologie : Feuilles de plante, Lycopersicon esculentum, Maladies des plantes, Noyau de la cellule, Tabac.
- métabolisme : Feuilles de plante, Lycopersicon esculentum, Noyau de la cellule, Protéines végétales, Tabac.
- pathogénicité : Phytophthora infestans.
- physiologie : Immunité des plantes, Mort cellulaire, Transduction du signal.

English descriptors

KwdEn :
- Cell Death (physiology), Cell Nucleus (metabolism), Cell Nucleus (microbiology), Lycopersicon esculentum (metabolism), Lycopersicon esculentum (microbiology), Phytophthora infestans (pathogenicity), Plant Diseases (microbiology), Plant Immunity (physiology), Plant Leaves (metabolism), Plant Leaves (microbiology), Plant Proteins (genetics), Plant Proteins (metabolism), Signal Transduction (genetics), Signal Transduction (physiology), Tobacco (metabolism), Tobacco (microbiology).
MESH :
- chemical , genetics : Plant Proteins.
- genetics : Signal Transduction.
- metabolism : Cell Nucleus, Lycopersicon esculentum, Plant Leaves, Plant Proteins, Tobacco.
- microbiology : Cell Nucleus, Lycopersicon esculentum, Plant Diseases, Plant Leaves, Tobacco.
- pathogenicity : Phytophthora infestans.
- physiology : Cell Death, Plant Immunity, Signal Transduction.

Abstract

The potato (Solanum tuberosum) blight pathogen Phytophthora infestans delivers Arg-X-Leu-Arg (RXLR) effector proteins into host cells to subvert plant immune responses and promote colonization. We show that transient expression and stable transgenic expression of the RXLR effector Pi22926 in Nicotiana benthamiana promotes leaf colonization by P. infestans. Pi22926 suppresses cell death triggered by coexpression of the Cladosporium fulvum avirulence protein Avr4 and the tomato (Solanum lycopersicum) resistance protein Cf4. Pi22926 interacts with a potato mitogen-activated protein kinase kinase kinase, StMAP3Kβ2, in the nucleoplasm. Virus-induced gene silencing (VIGS) of the ortholog NbMAP3Kβ2 in N. benthamiana enhances P. infestans colonization and attenuates Cf4/Avr4-induced cell death, indicating that this host protein is a positive regulator of immunity. Cell death induced by Cf4/Avr4 is dependent on NbMAP3Kε and NbMAP3Kβ2, indicating that these MAP3Ks function in the same signaling pathway. VIGS of NbMAP3Kβ2 does not compromise cell death triggered by overexpression of MAP3Kε. Similarly, VIGS of NbMAP3Kε does not attenuate cell death triggered by MAP3Kβ2, demonstrating that these MAP3K proteins function in parallel. In agreement, Pi22926 or another RXLR effector, PexRD2, only suppresses cell death triggered by expression of StMAP3Kβ2 or StMAP3Kε, respectively. Our data reveal that two P. infestans effectors, PexRD2 and Pi22926, promote P. infestans colonization by targeting MAP3K proteins that act in parallel in the same signal transduction pathway.

DOI: 10.1104/pp.18.00625
PubMed: 31217198
PubMed Central: PMC6670088

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000452
to stream Main, to step Curation: 000452

Le document en format XML

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 RXLR Effectors Target Parallel Steps in an Immune Signal Transduction Pathway.</title>
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 RXLR Effectors Target Parallel Steps in an Immune Signal Transduction Pathway.</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cell Death (physiology)</term>
<term>Cell Nucleus (metabolism)</term>
<term>Cell Nucleus (microbiology)</term>
<term>Lycopersicon esculentum (metabolism)</term>
<term>Lycopersicon esculentum (microbiology)</term>
<term>Phytophthora infestans (pathogenicity)</term>
<term>Plant Diseases (microbiology)</term>
<term>Plant Immunity (physiology)</term>
<term>Plant Leaves (metabolism)</term>
<term>Plant Leaves (microbiology)</term>
<term>Plant Proteins (genetics)</term>
<term>Plant Proteins (metabolism)</term>
<term>Signal Transduction (genetics)</term>
<term>Signal Transduction (physiology)</term>
<term>Tobacco (metabolism)</term>
<term>Tobacco (microbiology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Feuilles de plante (microbiologie)</term>
<term>Feuilles de plante (métabolisme)</term>
<term>Immunité des plantes (physiologie)</term>
<term>Lycopersicon esculentum (microbiologie)</term>
<term>Lycopersicon esculentum (métabolisme)</term>
<term>Maladies des plantes (microbiologie)</term>
<term>Mort cellulaire (physiologie)</term>
<term>Noyau de la cellule (microbiologie)</term>
<term>Noyau de la cellule (métabolisme)</term>
<term>Phytophthora infestans (pathogénicité)</term>
<term>Protéines végétales (génétique)</term>
<term>Protéines végétales (métabolisme)</term>
<term>Tabac (microbiologie)</term>
<term>Tabac (métabolisme)</term>
<term>Transduction du signal (génétique)</term>
<term>Transduction du signal (physiologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Plant Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Signal Transduction</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Protéines végétales</term>
<term>Transduction du signal</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Cell Nucleus</term>
<term>Lycopersicon esculentum</term>
<term>Plant Leaves</term>
<term>Plant Proteins</term>
<term>Tobacco</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Feuilles de plante</term>
<term>Lycopersicon esculentum</term>
<term>Maladies des plantes</term>
<term>Noyau de la cellule</term>
<term>Tabac</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Cell Nucleus</term>
<term>Lycopersicon esculentum</term>
<term>Plant Diseases</term>
<term>Plant Leaves</term>
<term>Tobacco</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Feuilles de plante</term>
<term>Lycopersicon esculentum</term>
<term>Noyau de la cellule</term>
<term>Protéines végétales</term>
<term>Tabac</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Phytophthora infestans</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Phytophthora infestans</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Immunité des plantes</term>
<term>Mort cellulaire</term>
<term>Transduction du signal</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Cell Death</term>
<term>Plant Immunity</term>
<term>Signal Transduction</term>
</keywords>
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<front><div type="abstract" xml:lang="en">The potato (<i>Solanum tuberosum</i>
) blight pathogen <i>Phytophthora infestans</i>
 delivers Arg-X-Leu-Arg (RXLR) effector proteins into host cells to subvert plant immune responses and promote colonization. We show that transient expression and stable transgenic expression of the RXLR effector Pi22926 in <i>Nicotiana benthamiana</i>
 promotes leaf colonization by <i>P. infestans.</i>
 Pi22926 suppresses cell death triggered by coexpression of the <i>Cladosporium fulvum</i>
 avirulence protein Avr4 and the tomato (<i>Solanum lycopersicum</i>
) resistance protein Cf4. Pi22926 interacts with a potato mitogen-activated protein kinase kinase kinase, StMAP3Kβ2, in the nucleoplasm. Virus-induced gene silencing (VIGS) of the ortholog <i>NbMAP3Kβ2</i>
 in <i>N. benthamiana</i>
 enhances <i>P. infestans</i>
 colonization and attenuates Cf4/Avr4-induced cell death, indicating that this host protein is a positive regulator of immunity. Cell death induced by Cf4/Avr4 is dependent on NbMAP3Kε and NbMAP3Kβ2, indicating that these MAP3Ks function in the same signaling pathway. VIGS of <i>NbMAP3Kβ2</i>
 does not compromise cell death triggered by overexpression of MAP3Kε. Similarly, VIGS of <i>NbMAP3Kε</i>
 does not attenuate cell death triggered by MAP3Kβ2, demonstrating that these MAP3K proteins function in parallel. In agreement, Pi22926 or another RXLR effector, PexRD2, only suppresses cell death triggered by expression of StMAP3Kβ2 or StMAP3Kε, respectively. Our data reveal that two <i>P. infestans</i>
 effectors, PexRD2 and Pi22926, promote <i>P. infestans</i>
 colonization by targeting MAP3K proteins that act in parallel in the same signal transduction pathway.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">31217198</PMID>
<DateCompleted><Year>2020</Year>
<Month>08</Month>
<Day>24</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>08</Month>
<Day>24</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1532-2548</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>180</Volume>
<Issue>4</Issue>
<PubDate><Year>2019</Year>
<Month>08</Month>
</PubDate>
</JournalIssue>
<Title>Plant physiology</Title>
<ISOAbbreviation>Plant Physiol</ISOAbbreviation>
</Journal>
<ArticleTitle><i>Phytophthora infestans</i>
 RXLR Effectors Target Parallel Steps in an Immune Signal Transduction Pathway.</ArticleTitle>
<Pagination><MedlinePgn>2227-2239</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1104/pp.18.00625</ELocationID>
<Abstract><AbstractText>The potato (<i>Solanum tuberosum</i>
) blight pathogen <i>Phytophthora infestans</i>
 delivers Arg-X-Leu-Arg (RXLR) effector proteins into host cells to subvert plant immune responses and promote colonization. We show that transient expression and stable transgenic expression of the RXLR effector Pi22926 in <i>Nicotiana benthamiana</i>
 promotes leaf colonization by <i>P. infestans.</i>
 Pi22926 suppresses cell death triggered by coexpression of the <i>Cladosporium fulvum</i>
 avirulence protein Avr4 and the tomato (<i>Solanum lycopersicum</i>
) resistance protein Cf4. Pi22926 interacts with a potato mitogen-activated protein kinase kinase kinase, StMAP3Kβ2, in the nucleoplasm. Virus-induced gene silencing (VIGS) of the ortholog <i>NbMAP3Kβ2</i>
 in <i>N. benthamiana</i>
 enhances <i>P. infestans</i>
 colonization and attenuates Cf4/Avr4-induced cell death, indicating that this host protein is a positive regulator of immunity. Cell death induced by Cf4/Avr4 is dependent on NbMAP3Kε and NbMAP3Kβ2, indicating that these MAP3Ks function in the same signaling pathway. VIGS of <i>NbMAP3Kβ2</i>
 does not compromise cell death triggered by overexpression of MAP3Kε. Similarly, VIGS of <i>NbMAP3Kε</i>
 does not attenuate cell death triggered by MAP3Kβ2, demonstrating that these MAP3K proteins function in parallel. In agreement, Pi22926 or another RXLR effector, PexRD2, only suppresses cell death triggered by expression of StMAP3Kβ2 or StMAP3Kε, respectively. Our data reveal that two <i>P. infestans</i>
 effectors, PexRD2 and Pi22926, promote <i>P. infestans</i>
 colonization by targeting MAP3K proteins that act in parallel in the same signal transduction pathway.</AbstractText>
<CopyrightInformation>© 2019 American Society of Plant Biologists. All Rights Reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ren</LastName>
<ForeName>Yajuan</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Key Laboratory of Potato Biology and Biotechnology, Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University (HZAU), Wuhan 430070, People's Republic of China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Key Laboratory of Horticultural Plant Biology (HZAU), Ministry of Education, Huazhong Agricultural University, Wuhan 430070, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Armstrong</LastName>
<ForeName>Miles</ForeName>
<Initials>M</Initials>
<Identifier Source="ORCID">0000-0002-9441-476X</Identifier>
<AffiliationInfo><Affiliation>Division of Plant Sciences, School of Life Science, University of Dundee (at James Hutton Institute), Invergowrie, Dundee DD2 5DA, United Kingdom.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Cell and Molecular Sciences, James Hutton Institute, Invergowrie, Dundee DD2 5DA, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Qi</LastName>
<ForeName>Yetong</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Key Laboratory of Potato Biology and Biotechnology, Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University (HZAU), Wuhan 430070, People's Republic of China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Key Laboratory of Horticultural Plant Biology (HZAU), Ministry of Education, Huazhong Agricultural University, Wuhan 430070, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>McLellan</LastName>
<ForeName>Hazel</ForeName>
<Initials>H</Initials>
<Identifier Source="ORCID">0000-0003-4490-7053</Identifier>
</Author>
<Author ValidYN="Y"><LastName>Zhong</LastName>
<ForeName>Cheng</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Key Laboratory of Potato Biology and Biotechnology, Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University (HZAU), Wuhan 430070, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Du</LastName>
<ForeName>Bowen</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Key Laboratory of Potato Biology and Biotechnology, Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University (HZAU), Wuhan 430070, People's Republic of China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Key Laboratory of Horticultural Plant Biology (HZAU), Ministry of Education, Huazhong Agricultural University, Wuhan 430070, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Birch</LastName>
<ForeName>Paul R J</ForeName>
<Initials>PRJ</Initials>
<Identifier Source="ORCID">0000-0002-6559-3746</Identifier>
<AffiliationInfo><Affiliation>Division of Plant Sciences, School of Life Science, University of Dundee (at James Hutton Institute), Invergowrie, Dundee DD2 5DA, United Kingdom.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Cell and Molecular Sciences, James Hutton Institute, Invergowrie, Dundee DD2 5DA, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tian</LastName>
<ForeName>Zhendong</ForeName>
<Initials>Z</Initials>
<Identifier Source="ORCID">0000-0002-3271-5372</Identifier>
<AffiliationInfo><Affiliation>Key Laboratory of Potato Biology and Biotechnology, Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University (HZAU), Wuhan 430070, People's Republic of China tianzhd@mail.hzau.edu.cn.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Key Laboratory of Horticultural Plant Biology (HZAU), Ministry of Education, Huazhong Agricultural University, Wuhan 430070, People's Republic of China.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>BB/G015244/1</GrantID>
<Acronym>BB_</Acronym>
<Agency>Biotechnology and Biological Sciences Research Council</Agency>
<Country>United Kingdom</Country>
</Grant>
<Grant><GrantID>BB/L026880/1</GrantID>
<Acronym>BB_</Acronym>
<Agency>Biotechnology and Biological Sciences Research Council</Agency>
<Country>United Kingdom</Country>
</Grant>
<Grant><GrantID>BB/K018183/1</GrantID>
<Acronym>BB_</Acronym>
<Agency>Biotechnology and Biological Sciences Research Council</Agency>
<Country>United Kingdom</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2019</Year>
<Month>06</Month>
<Day>19</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Plant Physiol</MedlineTA>
<NlmUniqueID>0401224</NlmUniqueID>
<ISSNLinking>0032-0889</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D010940">Plant Proteins</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D016923" MajorTopicYN="N">Cell Death</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
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<MeshHeading><DescriptorName UI="D018551" MajorTopicYN="N">Lycopersicon esculentum</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D055750" MajorTopicYN="N">Phytophthora infestans</DescriptorName>
<QualifierName UI="Q000472" MajorTopicYN="Y">pathogenicity</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010935" MajorTopicYN="N">Plant Diseases</DescriptorName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D057865" MajorTopicYN="N">Plant Immunity</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018515" MajorTopicYN="N">Plant Leaves</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
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<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015398" MajorTopicYN="N">Signal Transduction</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014026" MajorTopicYN="N">Tobacco</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
</MeshHeadingList>
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<ArticleIdList><ArticleId IdType="pubmed">31217198</ArticleId>
<ArticleId IdType="pii">pp.18.00625</ArticleId>
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</ArticleIdList>
<ReferenceList><Reference><Citation>J Exp Bot. 2019 Jan 1;70(1):343-356</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30329083</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2008 May;20(5):1390-406</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18515503</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2014 Mar;26(3):1345-59</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24632534</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2011 Jul 29;333(6042):596-601</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21798943</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2008 Jul;20(7):1930-47</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18621946</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Dev Cell. 2002 Aug;3(2):291-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12194859</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Trends Plant Sci. 2002 Jul;7(7):301-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12119167</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2018 Jul;30(7):1543-1561</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29871986</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2005 May 24;102(21):7766-71</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15894622</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Plant Pathol. 2015 May;16(4):413-34</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25178392</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2009 Sep 17;461(7262):393-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19741609</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2006 Nov 16;444(7117):323-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17108957</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 2018 May;177(1):398-410</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29588335</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Front Plant Sci. 2017 Dec 19;8:2155</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29312401</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Host Microbe. 2012 Oct 18;12(4):484-95</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23084917</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2010 May 25;107(21):9909-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20457921</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Annu Rev Phytopathol. 2016 Aug 4;54:419-41</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27359369</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 2003 Dec;36(6):905-17</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14675454</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Plant Biol. 2005 Oct;8(5):541-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16043387</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>mBio. 2018 Aug 28;9(4):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30154258</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Plant Biol. 2009 Aug;12(4):421-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19608449</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO Rep. 2018 Jul;19(7):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29789386</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):373-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11114160</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Host Microbe. 2014 Sep 10;16(3):364-75</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25211078</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 2007 Feb;143(2):661-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17142480</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2014 Apr 24;10(4):e1004057</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24763622</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biochem J. 2008 Jul 15;413(2):217-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18570633</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Host Microbe. 2010 Feb 18;7(2):164-75</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20159621</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Plant. 2015 Sep;8(9):1385-95</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25936676</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2012;8(10):e1002940</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23055926</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 1998 Sep;10(9):1413-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9724689</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Plant Microbe Interact. 2015 Oct;28(10):1063-72</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26125490</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO J. 2002 Sep 2;21(17):4511-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12198153</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2007 Nov 1;450(7166):115-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17914356</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2013;9(10):e1003670</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24130484</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 2010 Nov;64(3):379-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21049563</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Host Microbe. 2017 Mar 8;21(3):270-273</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28279328</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell. 2006 Feb 24;124(4):803-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16497589</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Res. 2008 Dec;18(12):1190-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18982020</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Microbiol. 2016 Dec;34:127-135</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27723513</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Rev Genet. 2010 Aug;11(8):539-48</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20585331</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMC Plant Biol. 2012 Jul 08;12:103</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22770370</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Rev Immunol. 2016 Sep;16(9):537-52</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27477127</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 2002 May;30(4):415-29</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12028572</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>New Phytol. 2017 Oct;216(1):205-215</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28758684</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 2016 May;171(1):645-57</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26966171</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMC Genomics. 2017 Feb 23;18(1):198</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28228125</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Microbiol. 2011 Feb;14(1):39-46</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21227738</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Trends Plant Sci. 2012 Nov;17(11):644-55</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22796464</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO J. 2004 Aug 4;23(15):3072-82</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15272302</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Royaume-Uni</li>
<li>République populaire de Chine</li>
</country>
<region><li>Hubei</li>
</region>
<settlement><li>Wuhan</li>
</settlement>
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<tree><noCountry><name sortKey="Mclellan, Hazel" sort="Mclellan, Hazel" uniqKey="Mclellan H" first="Hazel" last="Mclellan">Hazel Mclellan</name>
</noCountry>
<country name="République populaire de Chine"><region name="Hubei"><name sortKey="Ren, Yajuan" sort="Ren, Yajuan" uniqKey="Ren Y" first="Yajuan" last="Ren">Yajuan Ren</name>
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<name sortKey="Du, Bowen" sort="Du, Bowen" uniqKey="Du B" first="Bowen" last="Du">Bowen Du</name>
<name sortKey="Du, Bowen" sort="Du, Bowen" uniqKey="Du B" first="Bowen" last="Du">Bowen Du</name>
<name sortKey="Qi, Yetong" sort="Qi, Yetong" uniqKey="Qi Y" first="Yetong" last="Qi">Yetong Qi</name>
<name sortKey="Qi, Yetong" sort="Qi, Yetong" uniqKey="Qi Y" first="Yetong" last="Qi">Yetong Qi</name>
<name sortKey="Ren, Yajuan" sort="Ren, Yajuan" uniqKey="Ren Y" first="Yajuan" last="Ren">Yajuan Ren</name>
<name sortKey="Tian, Zhendong" sort="Tian, Zhendong" uniqKey="Tian Z" first="Zhendong" last="Tian">Zhendong Tian</name>
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<country name="Royaume-Uni"><noRegion><name sortKey="Armstrong, Miles" sort="Armstrong, Miles" uniqKey="Armstrong M" first="Miles" last="Armstrong">Miles Armstrong</name>
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<name sortKey="Armstrong, Miles" sort="Armstrong, Miles" uniqKey="Armstrong M" first="Miles" last="Armstrong">Miles Armstrong</name>
<name sortKey="Birch, Paul R J" sort="Birch, Paul R J" uniqKey="Birch P" first="Paul R J" last="Birch">Paul R J. Birch</name>
<name sortKey="Birch, Paul R J" sort="Birch, Paul R J" uniqKey="Birch P" first="Paul R J" last="Birch">Paul R J. Birch</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Bois/explor/PhytophthoraV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000606 | SxmlIndent | more

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Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Bois
   |area=    PhytophthoraV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:31217198
   |texte=   Phytophthora infestans RXLR Effectors Target Parallel Steps in an Immune Signal Transduction Pathway.
}}

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HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:31217198" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a PhytophthoraV1

This area was generated with Dilib version V0.6.38.
Data generation: Fri Nov 20 11:20:57 2020. Site generation: Wed Mar 6 16:48:20 2024

	Serveur d'exploration Phytophthora
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration Phytophthora

Phytophthora infestans RXLR Effectors Target Parallel Steps in an Immune Signal Transduction Pathway.

Phytophthora infestans RXLR Effectors Target Parallel Steps in an Immune Signal Transduction Pathway.

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Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki